Parkinson’s Disease: The Wearing-Off Effect

Medications for Parkinson’s disease work very well. But symptoms can creep back when they wear off.  This is known as “The Wearing-Off Effect.”

Over the course of Parkinson’s Disease (PD), a substantial number of patients develop a wearing-off effect which refers to the fact that the benefits you receive from your dopaminergic medications wear off before you are due to receive your next dose. This means you may go for a period of time with relatively uncontrolled motor symptoms.

If your Parkinson’s medication is wearing off, consider participating in a clinical trial.  Visit to learn about ongoing clinical trials for Parkinson’s.

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